|
|
3,7-dimethyl-6-octenoate + CoA + ATP <=> citronellyl-CoA + AMP + diphosphate
|
6.2.1
|
–
|
| |
KEGG:
R08088
MetaCyc:
RXN-11914
|
|
|
|
5-methylhex-4-enoyl-CoA + FAD <=> (2E)-5-methylhexa-2,4-dienoyl-CoA + FADH2
|
1.3.99
|
–
|
| |
KEGG:
R08092
|
|
|
|
3-Hydroxy-3-(4-methylpent-3-en-1-yl)glutaryl-CoA <=> 7-methyl-3-oxooct-6-enoyl-CoA + acetate
|
4.1.3.26
3-hydroxy-3-isohexenylglutaryl-CoA lyase
4.1.3.4
hydroxymethylglutaryl-CoA lyase
|
–
–
|
| |
BRENDA:
BR387
KEGG:
R08090
MetaCyc:
4.1.3.26-RXN
|
|
|
|
citronellol + NADP+ <=> (R)-citronellal + NADPH + H+
|
1.1.1.183
geraniol dehydrogenase (NADP+)
|
–
|
| |
KEGG:
R08084
|
|
|
|
citronellol + NAD+ <=> (R)-citronellal + NADH + H+
|
1.1.1
|
–
|
| |
KEGG:
R10125
|
|
|
|
(-)-Citronellol + NADP+ <=> (3S)-3,7-dimethyloct-6-enal + NADPH + H+
|
1.1.1.183
geraniol dehydrogenase (NADP+)
|
–
|
| |
KEGG:
R08085
|
|
|
|
geraniol + NADP+ <=> citral + NADPH + H+
|
1.1.1.1
alcohol dehydrogenase
1.1.1.183
geraniol dehydrogenase (NADP+)
1.1.1.195
cinnamyl-alcohol dehydrogenase
1.1.1.216
farnesol dehydrogenase (NADP+)
1.1.1.324
8-hydroxygeraniol dehydrogenase
1.1.1.90
aryl-alcohol dehydrogenase
|
–
–
–
–
–
–
|
| |
BRENDA:
BR29240
KEGG:
R03581
MetaCyc:
GERANIOL-DEHYDROGENASE-RXN
SABIO-RK:
3364
|
|
|
|
7-methyl-3-oxooct-6-enoyl-CoA + CoA <=> 5-methylhex-4-enoyl-CoA + acetyl-CoA
|
2.3.1
2.3.1.16
acetyl-CoA C-acyltransferase
|
–
–
|
| |
BRENDA:
BS417874
KEGG:
R08091
MetaCyc:
RXN-11917
|
|
|
|
citral + NAD+ + H2O <=> trans-geranic_acid + NADH + H+
|
1.2.1.3
aldehyde dehydrogenase (NAD+)
1.2.1.36
retinal dehydrogenase
1.2.1.86
geranial dehydrogenase
1.2.1.94
farnesal dehydrogenase
|
–
–
–
–
|
| |
BRENDA:
BR50237
KEGG:
R08086
MetaCyc:
RXN-11970
SABIO-RK:
9881;
9889
|
|
|
|
citronellyl-CoA + acceptor <=> geranoyl-CoA + reduced_acceptor
|
1.3.99
|
–
|
| |
KEGG:
R08089
|
|
|
|
3-hydroxy-5-methylhex-4-enoyl-CoA + NAD+ <=> 5-methyl-3-oxo-4-hexenoyl-CoA + NADH + H+
|
1.1.1.35
3-hydroxyacyl-CoA dehydrogenase
|
–
|
| |
KEGG:
R08094
|
|
|
|
(3S)-3,7-dimethyloct-6-enal + NAD+ + H2O <=> 3,7-dimethyl-6-octenoate + NADH + H+
|
1.2.1
|
–
|
| |
KEGG:
R08096
|
|
|
|
trans-Geranyl-CoA <=> geranoyl-CoA
|
5.2.1
|
–
|
| |
KEGG:
R08098
|
|
|
|
geraniol + NAD+ <=> citral + NADH + H+
|
1.1.1.1
alcohol dehydrogenase
1.1.1.183
geraniol dehydrogenase (NADP+)
1.1.1.198
(+)-borneol dehydrogenase
1.1.1.347
geraniol dehydrogenase (NAD+)
1.1.1.90
aryl-alcohol dehydrogenase
|
–
–
–
–
–
|
| |
BRENDA:
BR50498
KEGG:
R10308
MetaCyc:
RXN-11968
SABIO-RK:
13273
|
|
|
|
(R)-citronellal + NAD+ + H2O <=> 3,7-dimethyl-6-octenoate + NADH + H+
|
1.2.1
|
–
|
| |
KEGG:
R08087
|
|
|
|
5-methyl-3-oxo-4-hexenoyl-CoA + CoA <=> 3-methylcrotonoyl-CoA + acetyl-CoA
|
2.3.1
2.3.1.16
acetyl-CoA C-acyltransferase
|
–
–
|
| |
BRENDA:
BS417867
KEGG:
R08095
MetaCyc:
RXN-11921
|
|
|
|
trans-geranic_acid + CoA <=> trans-Geranyl-CoA + H2O
|
2.8.3
|
–
|
| |
KEGG:
R08097
|
|
|
|
cis-geranyl-CoA + HCO3- + ATP <=> 3-(4-methylpent-3-en-1-yl)pent-2-enedioyl-CoA + phosphate + ADP + H+
|
6.4.1.5
geranoyl-CoA carboxylase
|
–
|
| |
BRENDA:
BR157
KEGG:
R03494
MetaCyc:
GERANOYL-COA-CARBOXYLASE-RXN
|
|
|
|
3-Hydroxy-3-(4-methylpent-3-en-1-yl)glutaryl-CoA <=> 3-(4-methylpent-3-en-1-yl)pent-2-enedioyl-CoA + H2O
|
4.2.1.57
isohexenylglutaconyl-CoA hydratase
|
–
|
| |
BRENDA:
BR435
KEGG:
R03493
MetaCyc:
ISOHEXENYLGLUTACONYL-COA-HYDRATASE-RXN
|
|
|
|
(-)-Citronellol + NAD+ <=> (3S)-3,7-dimethyloct-6-enal + NADH + H+
|
1.1.1
|
–
|
| |
KEGG:
R10126
|
|
|
|
citral <=> neral
|
not assigned
|
–
|
| |
KEGG:
R08099
MetaCyc:
RXN-9193
|
|
|
|
(2E)-5-methylhexa-2,4-dienoyl-CoA + H2O <=> 3-hydroxy-5-methylhex-4-enoyl-CoA
|
4.2.1
4.2.1.17
enoyl-CoA hydratase
|
–
–
|
| |
BRENDA:
BS417818
KEGG:
R08093
MetaCyc:
RXN-11919
|
|
|
|
nerol + NADP+ <=> neral + NADPH
|
1.1.1.183
geraniol dehydrogenase (NADP+)
1.1.1.216
farnesol dehydrogenase (NADP+)
1.1.1.324
8-hydroxygeraniol dehydrogenase
|
–
–
–
|
| |
BRENDA:
BS187445
KEGG:
R08083
SABIO-RK:
12960
|
|
